Evaluation of Clinical and Oral Findings in Patients with Epidermolysis bullosa

Introduction: Epidermolysis bullosa (EB) is a genetically inherited disease characterized by recurrent bullae and erosions on the skin with numerous signs of dental caries poor oral hygiene. The aim this study was to investigate general clinical findings patients EB. Materials Methods: In prospective study, family history 26 cases EB were evaluated. type EB, gender, age, parental consanguinity, caries, findings, distribution lesions presence associated anomalies, correlated gender recorded. Results: All had consanguinity siblings varying degrees. our malnutrition, anemia growth retardation, gastrointestinal system complications, hair thinning, hand nail deformity, ocular problems renal (in one case) observed variable frequencies. When intraoral investigated, extensive in all types, enamel hypoplasia junctional (JEB) tooth-root be extracted dystrophic (DEB), lesions, ankyloglossia, vestibular sulcus insufficiency, microstomia maxillary atrophy observed. Three restorative treatment case prosthetic rehabilitation. Conclusions: Oral involvement can seen frequencies depending severity disease. It may result from delayed rehabilitation due physical disabilities, limitations more pressing medical problems. Microstomy, pain mucosal restricted access mouth caused complications caloric needs individuals should determined, individual prophylaxis applied prevent formation protect teeth.